Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes. SYN: glomerular sclerosis. [glomerulus + G. sklerosis, hardness]
- diabetic g. proteinuria and ultimately, renal failure occuring in long standing diabetes and characterized by rounded hyaline or laminated nodules in the periphery of the glomeruli with capillary basement membrane thickening and increased mesangial matrix. SYN: intercapillary g..
- focal segmental g. segmental collapse of glomerular capillaries with thickened basement membranes and increased mesangial matrix; seen in some glomeruli of patients with nephrotic syndrome or mesangial proliferative glomerulonephritis.
- intercapillary g. SYN: diabetic g..
* * *
glo·mer·u·lo·scle·ro·sis -(y)ə-.lō-sklə-'rō-səs n, pl -ro·ses -.sēz nephrosclerosis involving the renal glomeruli
* * *
glo·mer·u·lo·scle·ro·sis (glo-mer″u-lo-sklə-roґsis) fibrosis and scarring with senescence of the renal glomeruli.Medical dictionary. 2011.