An analgesic, antipyretic, and anti-inflammatory nonsteroidal agent used in the management of rheumatoid arthritis and in the treatment of osteoarthritis, ankylosing spondylitis, and gout. It is also used to produce closure of a patent ductus arteriosus in infants.
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in·do·meth·a·cin .in-dō-'meth-ə-sən n an NSAID C19H16ClNO4 with analgesic and antipyretic properties used esp. to treat painful inflammatory conditions (as rheumatoid arthritis and osteoarthritis) see INDOCIN
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in·do·meth·a·cin (in″do-methґə-sin) [USP] a nonsteroidal antiinflammatory drug; used in the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gouty arthritis, other rheumatic and nonrheumatic inflammatory conditions, and dysmenorrhea, and the treatment and prophylaxis of vascular headaches; administered orally or rectally. It is also applied topically to the conjunctiva to prevent miosis during cataract surgery and to reduce the severity and occurrence of postoperative cystoid macular edema.Medical dictionary. 2011.