A cholesterol-lowering agent, isolated from a strain of Aspergillus terreus, that reduces both normal and elevated serum cholesterol. SYN: mevinolin.
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lov·a·stat·in 'lō-və-.stat-ən, 'ləv-ə- n a drug C24H36O8 that decreases the level of cholesterol in the bloodstream by inhibiting the liver enzyme that controls cholesterol synthesis and is used in the treatment of hypercholesterolemia see MEVACOR
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lo·va·stat·in (loґvə-stat″in) [USP] an inhibitor of HMG-CoA reductase, which can lower plasma levels of cholesterol and raise the plasma level of high-density lipoprotein C (HDL-C); used in the treatment of hypercholesterolemia and other forms of dyslipidemia and to reduce the risk of morbidity and mortality associated with atherosclerosis and coronary heart disease; administered orally.Medical dictionary. 2011.