1. The process of isolating a solid substance from solution by freezing the solution and evaporating the ice under vacuum. 2. The process of imparting lyophilic properties to a substance. SYN: freeze-drying.
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ly·oph·i·li·za·tion (li-of″ĭ-lĭ-zaґshən) the creation of a stable preparation of a biological substance (blood plasma, serum, etc.), by rapid freezing and dehydration of the frozen product under high vacuum. See also freeze-drying.Medical dictionary. 2011.