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sphin·go·my·elin·ase -'mī-ə-lə-.nās, -.nāz n any of several enzymes that catalyze the hydrolysis of sphingomyelin and are lacking in some metabolic deficiency diseases (as Niemann-Pick disease) in which sphingomyelin accumulates in bodily organs (as the spleen and liver)
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sphin·go·my·elin·ase (sfing″go-miґə-lin-ās) sphingomyelin phosphodiesterase.Medical dictionary. 2011.