The formal parent of the thromboxanes; prostanoic acid in which the –COOH has been reduced to –CH3 and an oxygen atom has been inserted between carbons 11 and 12.
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throm·box·ane thräm-'bäk-.sān n any of several substances that are produced esp. by platelets, are formed from endoperoxides, cause constriction of vascular and bronchial smooth muscle, and promote blood clotting
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throm·box·ane (throm-bokґsān) [thrombocyte + oxane ring] either of two compounds related to prostaglandins and derived from arachidonic acid. Thromboxane A2 (TXA2) is an extremely potent inducer of platelet aggregation and platelet release reactions and is also a vasoconstrictor; it is thus a physiologic antagonist of prostacyclin. It is synthesized by platelets and is very unstable, with a half-life of 30 seconds, undergoing nonenzymatic hydrolysis to thromboxane B2 (TXB2), which is inactive.Medical dictionary. 2011.