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a) the evolutionary change of one species into another
b) the conversion of one element or nuclide into another either naturally or artificially
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trans·mu·ta·tion (trans″mu-taґshən) 1. evolutionary change of one species into another. 2. the change of one chemical element into another; nucleonics, the changing of an atomic nucleus to one of a different atomic number by nuclear bombardment, causing rearrangement of the protons and neutrons.Medical dictionary. 2011.