- angiotensin receptor blockers agents, such as losartan, that bind with angiotensin receptors, thus preventing access of angiotensin II to the receptor and consequently reducing the vasoconstriction produced by this agonist; used in the treatment of hypertension.
- calcium channel b. a class of drugs with the capacity to prevent calcium ions from passing through biologic membranes. These agents are used to treat hypertension, angina pectoris, and cardiac arrhythmias; examples include nifedipine, diltiazem, verapamil, amlodipene.
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block·er (blokґər) something that obstructs passage or activity. See also antagonist, and see blocking agent, under agent.Medical dictionary. 2011.